Rob J. de Boer |
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Estimating relative fitness from competition experiments
You have the number of mutant and wild type sequences at the start and at the end of a competition experiment. You also know the initial and the final viral load in your experiment. You may have a third group of unrelated mutants. This can be represented in the boxes total number. The total number of sequences will be more than the sum of the mutant and wild type sequences when the data involve more than two variants.