Theoretical Biology & Bioinformatics

tree of life

Open positions:

PhD position Theoretical Immunology

We are looking for a PhD student (a Marie Curie Early Stage Researcher) with a keen interest in combining bioinformatics and mathematical modelling within immunology. Our aim is to analyze data on the dynamics and repertoires of memory T cell subsets collected from the blood and the bone marrow of volunteers. The experimental data are collected by two other PhD students in Utrecht, and you are expected to collaborate closely with them. Our main goal is to determine in which tissues T cell memory is maintained, by which subsets of memory T cells, how long these cells live, and where most of them are produced. Answering these questions requires modeling the kinetic data, and bioinformatically analyzing the repertoire data. At Utrecht University we have a long-standing collaboration between modelers, bioinformaticians and immunologists, which is formalized in the form of the Utrecht Center for Quantitative Immunology (UCQI). This is an inspiring enviroment where theoreticians and immunologists have learned to speak each other's language and collaborate intensively.

This PhD project is funded by QuanTII, which is a Marie Sklodowska-Curie Innovative Training Network. Its primary objective is to train a new generation of quantitative immunologists, who will be able to address challenges arising in T cell Immunology and Immunotherapy. The QuanTII Network will train a total of 15 Early Stage Researchers (ESRs) across Europe, bringing together renowned European experimental and theoretical scientists from private and academic institutions. The QuanTII Fellowship offers a highly competitive and attractive salary and working conditions. The successful candidate will receive a salary in accordance with the Marie Sklodowska Curie regulations for early stage researchers. Additional allowances to cover living costs and may be available. Candidates must have experience with mathematical modeling and/or bioinformatics, and have to be interested in biology (and preferably immunology). You will work in a Theoretical Biology and Bioinformatics (TBB) group working on various areas in biology.

To be eligible for this position you must have an MSc degree in an appropriate discipline (such as Biology, Math or Physics), which you obtained no more than 4 years ago. You should not have been resident or have carried out your main activity (work, studies, etc.) in the Netherlands for more than 12 months in the past 3 years. These eligibility requirements are stipulated by the funder and are non-negotiable. Please do not apply if you do not meet them.

How to apply

Please send your CV, along with a cover letter outlining your specific qualifications and motivation for this position, including contact information for at least one reference to: Prof.dr. Rob J. de Boer ( no later than August 18, 2018

PhD position NIOZ

There is a PhD position available to study “Modelling causal interactions between marine microbes” at our NIOZ collaborators: