Theoretical Biology & Bioinformatics

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Rob J. de Boer

Rob J. de Boer

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Estimating relative fitness from competition experiments

You have the number of mutant and wild type sequences at the start and at the end of a competition experiment. You also know the initial and the final viral load in your experiment. You may have a third group of unrelated mutants. This can be represented in the boxes total number. The total number of sequences will be more than the sum of the mutant and wild type sequences when the data involve more than two variants.

Length of experiment in days: Death rate of infected cells (delta):
Initial virus value: Final virus value:
Initial number of mutants: Final number of mutants:
Initial number of wild type: Final number of wild type:
Initial number of sequences: Final number of sequences:
Dilution factor (1 means no dilution):